Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Synthetic Route of 2576-47-8.
Bahadori, Mehrnaz;Marandi, Afsaneh;Tangestaninejad, Shahram;Moghadam, Majid;Mirkhani, Valiollah;Mohammadpoor-Baltork, Iraj research published 《 Ionic Liquid-Decorated MIL-101(Cr) via Covalent and Coordination Bonds for Efficient Solvent-Free CO2 Conversion and CO2 Capture at Low Pressure》, the research content is summarized as follows. An imidazolium-based ionic liquid was embedded into MIL-101(Cr) via coordinate and covalent bonds to synthesize heterogeneous catalysts for efficient CO2 capture at low pressure and CO2 fixation with epoxides. In MIL-IL(A), the ionic liquid was coordinated to Cr centers, while in MIL-IL(B), the ionic liquid was attached to MIL-101(Cr) via a covalent bond. These two materials were used for CO2 capture at p/p0 = 0.033 and 0°C. The results showed that the CO2 absorbing capacity for MIL-IL(A) and MIL-IL(B) is 5.46 and 7.84 times higher than that of the parent MOF, resp. The ionic liquid loading was measured by IC, CHN, and thermogravimetric anal. (TGA). Furthermore, the catalytic activity of both catalysts was checked in the cycloaddition of CO2 to epoxides in the absence of any cocatalyst and under solvent-free conditions. A firm bond between the ionic liquid and the framework in MIL-IL(B) made it a recyclable heterogeneous catalyst for CO2 fixation with epoxides. The anal. techniques confirmed the grafting of ionic liquid on the MOF structure, and the framework remained intact after 5 cycles in the cycloaddition of CO2 to styrene epoxide.
Synthetic Route of 2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary