Organic compounds having carbon bonded to bromine are called organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Synthetic Route of 823-78-9.
Asadizadeh, Saeedeh;Sohrabi, Marzieh;Mereiter, Kurt;Farrokhpour, Hossein;Meghdadi, Soraia;Amirnasr, Mehdi research published 《 Novel octanuclear copper(I) clusters [Cu8{(N)-(μ4-S)}4(μ3-I)2I2(PPh3)2] produced via reductive S-S bond cleavage of disulfide Schiff base ligands and their use as efficient heterogeneous catalysts in CuAAC click reaction》, the research content is summarized as follows. Herein, the facile one pot synthesis of novel octanuclear copper(I) complexes, [Cu8{(N)-(μ4-S)}4(μ3-I)2I2(PPh3)2], by the reaction of copper(I) iodide and disulfide Schiff base mols. (R-CH=NPhSSPh-N=CH-R, RMePh = 4-MePh, RMeOPh = 4-MeOPh, RMeSPh = 4-MeSPh, RBrPh = 4-BrPh, and RFur = 2-furan) in the presence of PPh3 in dichloromethane-acetonitrile or chloroform-acetonitrile solution under ambient conditions is reported. Single-crystal X-ray structure analyses of these clusters confirm the presence of Cu8S4I4 core stabilized by the chelating Schiff base thiolate fragment R-CH=N-Ph-S– produced by the reductive cleavage of disulfide bond, I–, and PPh3. DFT calculations have been performed to describe a speculative mechanism of cluster formation. The octanuclear clusters [Cu8{(N)-(μ4-S)}4(μ3-I)2I2(PPh3)2] have been exploited as efficient heterogeneous catalysts for the green synthesis of 1,2,3-triazoles from NaN3, alkyl halides, and alkyne derivatives (CuAAC reaction) under mild conditions.
823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.
3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.
3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Synthetic Route of 823-78-9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary