Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Application In Synthesis of 2576-47-8.
Aldahdooh, Mohammed K.;Ali, Shaikh A. research published 《 Synthesis and application of a poly(bis-zwitterion) containing chelating motifs of N-(2-aminoethyl)iminodiacetic acid》, the research content is summarized as follows. A bis-cationic (+ +) diallyl monomer [(H2C=CHCH2)2NH+(CH2)2NH+(CH2CO2H)2·2Cl–] (I) was prepared by a one-pot, two-step reaction of 2-bromoethylamine hydrobromide, Et bromoacetate and diallylamine to generate [(H2C=CHCH2)2N(CH2)2N(CH2CO2Et)2] followed by ester hydrolysis. I underwent cyclopolymn. to afford a unique poly(bis-zwitterion) (PBZ) (± ±) II, containing repeating unit embedded with chelating motifs of N-(2-aminoethyl)iminodiacetic acid in bis-zwitterionic form NH+(CH2)2NH+(CH2CO–2)2. Electroneutral II was found to be water-insoluble, while salts like NaCl imparted water-solubility The polymer was soluble outside a pH window of 1.5-3.5 owing to the equilibration of pH-responsive II to charge-imbalanced polymer chain. The ‘apparent’ pKas of the two NH+ centers were determined to be 5.89 and 10.57. At 2.5 ppm concentration, antiscalant PBZ II imparted 100% inhibition of CaSO4 scale formation for 30 min from its supersaturated solution, while at 20 ppm concentration aided by KI, it demonstrated an outstanding synergistic 99% inhibition of mild steel corrosion in 1 M HCl.
Application In Synthesis of 2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary