Cas: 611-75-6 | Wu, Jingfangpublished an article in 2015

2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) (BHH; 250μM; 24 hours) also significantly attenuates HGF-induced invasion of LNCaP and C4-2B cells that natively express TMPRSS2. No significant toxicity is observed over a 48-hour period exposing LNCaP, DU145, PC3, or HepG2 cells to Bromhexine hydrochloride concentrations ranging from 0μM to 250μM. Bromhexine hydrochloride exposure does not induce cell death or substantially suppress the growth of DU145 cells.Bromhexine hydrochloride (20 μM; 48 h) inhibits dendritic cells infection with HIV-1.Category: bromides-buliding-blocks

Category: bromides-buliding-blocks《HPLC simultaneous determination of four active components in sulfamethoxazole, trimethoprim, bromhexine hydrochloride and clorprenaline hydrochloride capsules》 was published in 2015. The authors were Wu, Jingfang;Li, Zhifang, and the article was included in《Zhongguo Yaopin Biaozhun》. The author mentioned the following in the article:

Objective: To establish an HPLC method for content determination of four active components in Sulfamethoxazole, Trimethoprim, Bromhexine Hydrochloride and Clorprenaline Hydrochloride Capsules. Methods: The HPLC anal. was performed on an Ecosil-C18 (4.6 mm × 250 mm, 5 μm) column. The mobile phase was consisted of acetonitrile and 0.0015 mol·L-1 sodium dodecyl sulfate of 0.1% triethylamine solution (pH was adjusted to 3.0 by phosphoric acid) (52:48) at the flow rate of 1.0 mL·min-1. The detected wavelength was set at 215 nm. Results: Four active components were separated completely in 10 min, and had good linear relationship (r>0.9999) and recoveries (98.85%-99.58%) in their resp. detection scopes. Conclusion: The method can be applied for simultaneous determination of four active components in Sulfamethoxazole, Trimethoprim, Bromhexine Hydrochloride and Clorprenaline Hydrochloride Capsules. The experimental procedure involved many compounds, such as 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride (cas: 611-75-6) .

2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) (BHH; 250μM; 24 hours) also significantly attenuates HGF-induced invasion of LNCaP and C4-2B cells that natively express TMPRSS2. No significant toxicity is observed over a 48-hour period exposing LNCaP, DU145, PC3, or HepG2 cells to Bromhexine hydrochloride concentrations ranging from 0μM to 250μM. Bromhexine hydrochloride exposure does not induce cell death or substantially suppress the growth of DU145 cells.Bromhexine hydrochloride (20 μM; 48 h) inhibits dendritic cells infection with HIV-1.Category: bromides-buliding-blocks

Reference:
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