Cas: 611-75-6 was involved in experiment | Zhongguo Yiyao Gongye Zazhi 2013

2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) (BHH; 250μM; 24 hours) also significantly attenuates HGF-induced invasion of LNCaP and C4-2B cells that natively express TMPRSS2. No significant toxicity is observed over a 48-hour period exposing LNCaP, DU145, PC3, or HepG2 cells to Bromhexine hydrochloride concentrations ranging from 0μM to 250μM. Bromhexine hydrochloride exposure does not induce cell death or substantially suppress the growth of DU145 cells.Bromhexine hydrochloride (20 μM; 48 h) inhibits dendritic cells infection with HIV-1.Formula: C14H21Br2ClN2

Formula: C14H21Br2ClN2In 2013, Pu, Jiekun;Zhang, Kai;Hao, Xiaofei;Niu, Guizhen;Du, Yumin published 《Synthesis of bromhexine hydrochloride》. 《Zhongguo Yiyao Gongye Zazhi》published the findings. The article contains the following contents:

Bromhexine hydrochloride was synthesized from 2-amino-3,5-dibromobenzaldehyde by reduction with NaBH4 and chlorination with SOCl2 to give 2,4-dibromo-6-chloromethylaniline, which was subjected to amination with N-methylcyclohexylamine and salt formation. The overall yield was about 57%. The experimental procedure involved many compounds, such as 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride (cas: 611-75-6) .

2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) (BHH; 250μM; 24 hours) also significantly attenuates HGF-induced invasion of LNCaP and C4-2B cells that natively express TMPRSS2. No significant toxicity is observed over a 48-hour period exposing LNCaP, DU145, PC3, or HepG2 cells to Bromhexine hydrochloride concentrations ranging from 0μM to 250μM. Bromhexine hydrochloride exposure does not induce cell death or substantially suppress the growth of DU145 cells.Bromhexine hydrochloride (20 μM; 48 h) inhibits dendritic cells infection with HIV-1.Formula: C14H21Br2ClN2

Reference:
Bromide – Wikipedia,
bromide – Wiktionary