Application In Synthesis of 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochlorideIn 2015, Attia, Khalid Abdelsalam M.;Nassar, Mohammed W. I.;Osman, Ayman published 《Different chemometric models applied for the simultaneous determination of certain drugs acting on respiratory system》. 《European Journal of Biomedical and Pharmaceutical Sciences》published the findings. The article contains the following contents:
Different Chemometric models were applied for the quant. anal. of Salbutamol (SL) and bromhexine (BH) in binary mixture, namely, Classical Least Square (CLS), Principle Component Regression (PCR), Artificial Neural Networks (ANN) as advanced model And Genetic algorithm- Artificial Neural Networks GA-ANN. The methods were used for the quant. anal. of the drugs in raw materials and pharmaceutical dosage form via handling the UV spectral data. A 2-factor 5-level exptl. design was established resulting in 25 mixtures containing different ratios of the drugs. Thirteen mixtures were used as a calibration set and the other twelve mixtures were used as validation set to validate the prediction ability of the suggested methods. The experimental procedure involved many compounds, such as 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride (cas: 611-75-6) .
2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) is intended to support the body’s mechanisms for clearing mucus from the respiratory tract. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport.Application In Synthesis of 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride
Reference:
Bromide – Wikipedia,
bromide – Wiktionary