Application of 611-75-6《Determination of bromhexine at a glassy carbon paste electrode using differential pulse voltammetry and flow injection analysis with amperometric detection》 was published in 2015. The authors were Mika, Jan;Moreira, Josino C.;Nemeckova, Andrea;Zima, Jiri;Barek, Jiri;Dejmkova, Hana, and the article was included in《Monatshefte fuer Chemie》. The author mentioned the following in the article:
Abstract: New electrochem. methods for the determination of bromhexine based on differential pulse voltammetry (DPV) and flow injection anal. with amperometric detection (FIA-ED) were developed using a glassy carbon paste electrode. Optimal supporting electrolyte for DPV measurement was methanol/Britton-Robinson buffer pH 9 (80:20, volume/volume). In the case of FIA-ED, optimal conditions were as follows: detection potential +1.1 V, flow rate 1.0 cm3 min-1, injected volume 0.1 cm3, and carrier solution methanol-ten times diluted B-R buffer of pH 9 (80:20, volume/volume). Detection limit was 2.0 × 10-6 mol dm-3 for DPV and 3.1 × 10-7 mol dm-3 for FIA-ED. The applicability of the newly developed methods was verified by the determination of bromhexine in pharmaceutical preparations (tablets of Bromhexin-EGIS and Bromhexin 8 BC). To complete the study, the researchers used 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride (cas: 611-75-6) .
2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) is a mucolytic agent that exerts both a secretagogic action on submucosal glands and a mucolytic action toward acid glycoproteins inside cells. Bromhexine Hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm. OthersBromhexine is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine has antioxidant properties. Application of 611-75-6
Reference:
Bromide – Wikipedia,
bromide – Wiktionary