Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Circular dichroism of multi-component assemblies for chiral amine recognition and rapid ee determination.Electric Literature of C20H12Br2O2.
Upon mixing a chiral amine, enantiopure BINOL, and o-formyl Ph boronic acid, the three components assemble efficiently and rapidly into chiral host-guest structures that produce distinct CD signals for each enantiomer of the amine. Employing BINOL and two derivatives to create an array of receptors, the CD signals resulting from several α-chiral primary amines were processed by principal component anal. and linear discriminant anal. to give satisfactory discrimination of the amines studied. Not only was the system able to differentiate the analytes chemoselectively and enantioselectively, but it also allowed for the rapid determination of chiral amine ee values.
Different reactions of this compound((S)-3,3′-Dibromo-1,1′-bi-2-naphthol)Electric Literature of C20H12Br2O2 require different conditions, so the reaction conditions are very important.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary