Recommanded Product: 2645-22-9. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 4,4-Dipyridyl Disulfide, is researched, Molecular C10H8N2S2, CAS is 2645-22-9, about Copper-Catalyzed Cycloaddition of Heterobicyclic Alkenes with Diaryl Disulfides to Synthesize Dihydrobenzo[b]thiophene Derivatives.
A novel copper-catalyzed cycloaddition of diaryl disulfides RSSR (R = Ph, naphthalen-1-yl, pyridin-4-yl, etc.) to heterobicyclic alkenes I [R1 = H, F, Me, OMe; R2 = H, F, OMe; R3 = H, Me, C(O)OMe; R4 = H, Me, C(O)OMe; X = O, CH2, NTs, NBoc] has been developed. The C-S and C-C bonds can be formed simultaneously on the C=C bond of the olefins via a single-step cycloaddition to afford a series of 2,3-dihydrobenzo[b]thiophene derivatives II [R5 = H, F, OMe; R6 = H, OMe, Cl; R5R6 = -CH=CH-CH=CH-; R7 = H, F, Me, Ph, etc.; R8 = H, OMe, Cl; R7R8= -CH=CH-CH=CH-] and III. This reaction exhibits excellent diastereoselectivity and relatively broad substrate scope. Various functional groups attached to the substrates are tolerated in this protocol to give the corresponding exo adducts II and III in moderate yields.
《Copper-Catalyzed Cycloaddition of Heterobicyclic Alkenes with Diaryl Disulfides to Synthesize Dihydrobenzo[b]thiophene Derivatives》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(4,4-Dipyridyl Disulfide)Recommanded Product: 2645-22-9.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary