COA of Formula: C7H12O3. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Ethyl 3-Ethoxy-2-Propenoate, is researched, Molecular C7H12O3, CAS is 1001-26-9, about Elimination versus diastereoselective alkylation in homochiral 2-(β-ethoxycarbonyl) acetals. Author is Caballero, Mercedes; Garcia-Valverde, Maria; Pedrosa, Rafael; Vicente, Martina.
The reaction of the homochiral 2-(β-ethoxycarbonyl)dioxolane I derived from (-)-exo-camphanediol with Me iodide in the presence of one equivalent of LDA lead to the alkylated product in very good chem. yield and poor diastereomeric excess. 2-(β-Ethoxycarbonyl)-1,3-dioxanes II derived from 2,4-pentanediol behave in a different way, whereas the diequatorial form is alkylated in excellent chem. yield, the equatorial-axial diastereoisomer III yields a mixture of alkylation and elimination products.
Different reactions of this compound(Ethyl 3-Ethoxy-2-Propenoate)COA of Formula: C7H12O3 require different conditions, so the reaction conditions are very important.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary