Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Tetrahedron Letters called α-Alkylation of lithium dienolates derived from 3(2H)-furanones and related α,β-unsaturated carbonyl compounds, Author is Smith, Amos B. III; Scarborough, Robert M. Jr., which mentions a compound: 1001-26-9, SMILESS is O=C(OCC)/C=C/OCC, Molecular C7H12O3, Recommanded Product: 1001-26-9.
The regioselectivity was studied of the alkylation of the Li dienolates derived from 3(2H)-furanones and β-alkoxy-α,β-unsaturated carbonyl compounds by treatment with (Me2CH)2NLi in THF. Exclusive γ-alkylation was observed when the resulting dienolate contained a double bond exocyclic to the ring whereas no γ-alkylation occurred for substrates whose dienolate possessed an endocyclic or acyclic olefin. E.g., the dienolate I, derived from 2,2-dimethyl-5-isopropyl-3(2H)-furanone, reacted with MeI, CH2:CHCH2Br, Me(CH2)4I, or PhSeBr gave 75-93% γ-alkylated product whereas the dienolate derived from EtOCMe:CHCO2Et reacted with Me(CH2)4I to give 88% α-alkylated product.
Different reactions of this compound(Ethyl 3-Ethoxy-2-Propenoate)Recommanded Product: 1001-26-9 require different conditions, so the reaction conditions are very important.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary