Electric Literature of C20H12Br2O2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Copper-Complex-Catalyzed Asymmetric Aerobic Oxidative Cross Coupling of 2-Naphthols: Enantioselective Synthesis of 3,3′-Substituted C1-Symmetric BINOLs. Author is Tian, Jin-Miao; Wang, Ai-Fang; Yang, Ju-Song; Zhao, Xiao-Jing; Tu, Yong-Qiang; Zhang, Shu-Yu; Chen, Zhi-Min.
A novel chiral 1,5-N,N-bidentate ligand I based on a spirocyclic pyrrolidine oxazoline backbone was designed and prepared; it coordinates CuBr in situ to form an unprecedented catalyst that enables efficient oxidative cross-coupling of 2-naphthols II (R3 = CHO, PhOCO, 3-FC6H4OCO, CHO, etc., R4 = H; R3 = PhOCO, R4 = Me, Br, OMe) and III (R5 = Br, Cl, CHO, PhCH2O, etc., R6 = H; R5 = H, R6 = OMe). Air serves as an external oxidant and generates a series of C1-sym. chiral BINOL derivatives IV with high enantioselectivity (up to 99% ee) and good yield (up to 87%). This approach is tolerant of a broader substrates scope, particularly substrates bearing various 3- and 3′-substituents. A preliminary investigation using one of the obtained C1-sym. BINOL product IV (R3 = CHO; R4 = R6 = H; R5 = Br) as an organocatalyst exhibited better enantioselectivity than the previously reported organocatalyst for the asym. α-alkylation of di-Et 2-aminomalonate.
After consulting a lot of data, we found that this compound(119707-74-3)Electric Literature of C20H12Br2O2 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary