Category: bromides-buliding-blocks. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Effective BI-DIME Ligand for Suzuki-Miyaura Cross-Coupling Reactions in Water with 500 ppm Palladium Loading and Triton X. Author is Patel, Nitinchandra D.; Rivalti, Daniel; Buono, Frederic G.; Chatterjee, Arindom; Qu, Bo; Braith, Stefan; Desrosiers, Jean-Nicolas; Rodriguez, Sonia; Sieber, Joshua D.; Haddad, Nizar; Fandrick, Keith R.; Lee, Heewon; Yee, Nathan K.; Busacca, Carl A.; Senanayake, Chris H..
An efficient, sustainable, and broadly applicable procedure has been developed for Suzuki-Miyaura cross-coupling reactions in environmentally benign solvent (water) by employing as little as 500 ppm Pd(OAc)2 with a monophosphorus BI-DIME ligand in the presence of inexpensive and com. available nonionic surfactant Triton X-100. This method was applied to a broad range of functionalized reaction partners, thereby affording excellent yields of the coupling products, including active pharmaceutical ingredients (APIs). An interesting kinetic study by using reaction calorimetry is also presented, which describes the effect of reaction parameters that enabled the low catalyst loading.
After consulting a lot of data, we found that this compound(119707-74-3)Category: bromides-buliding-blocks can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary