In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called One-Pot Asymmetric Synthesis of Alkylidene 1-Alkylindan-1-ols Using Bronsted Acid and Palladium Catalysis, published in 2017-11-03, which mentions a compound: 119707-74-3, mainly applied to asym synthesis alkylmethyleneindanol Bronsted acid palladium catalysis; enantioselective allylboration Mizoroki Heck bromoaryl ketone, HPLC of Formula: 119707-74-3.
A one-pot catalytic enantioselective allylboration/Mizoroki-Heck reaction of 2-bromoaryl ketones has been developed for the asym. synthesis of 3-methyleneindanes bearing a tertiary alc. center. Bronsted acid-catalyzed allylboration with a chiral BINOL derivative was followed by a palladium-catalyzed Mizoroki-Heck cyclization, resulting in selective formation of the exo-alkene. This novel protocol provides a concise and scalable approach to 1-alkyl-3-methyleneindan-1-ols in high enantiomeric ratios (up to 96:4 er). The potential of these compounds as chiral building blocks was demonstrated with efficient transformation to optically active diol and amino alc. scaffolds.
The article 《One-Pot Asymmetric Synthesis of Alkylidene 1-Alkylindan-1-ols Using Bronsted Acid and Palladium Catalysis》 also mentions many details about this compound(119707-74-3)HPLC of Formula: 119707-74-3, you can pay attention to it, because details determine success or failure
Reference:
Bromide – Wikipedia,
bromide – Wiktionary