In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Asymmetric Propargylation of Ketones Using Allenylboronates Catalyzed by Chiral Biphenols, published in 2011-08-05, which mentions a compound: 119707-74-3, mainly applied to homopropargylic alc enantioselective preparation; ketone allenylboronate asym propargylation biphenol catalyst, Safety of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol.
Chiral biphenols catalyze the enantioselective asym. propargylation of ketones using allenylboronates. The reaction uses 10 mol % of 3,3′-Br2-BINOL as the catalyst and allenyldioxoborolane as the nucleophile, in the absence of solvent, and under microwave irradiation to afford the homopropargylic alc., e.g., I. The reaction products are obtained in good yields (60-98%) and high enantiomeric ratios (3:1-99:1). Diastereoselective propargylations using chiral racemic allenylboronates result in good diastereoselectivities (dr >86:14) and enantioselectivities (er >92:8) under the catalytic conditions.
The article 《Asymmetric Propargylation of Ketones Using Allenylboronates Catalyzed by Chiral Biphenols》 also mentions many details about this compound(119707-74-3)Safety of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, you can pay attention to it, because details determine success or failure
Reference:
Bromide – Wikipedia,
bromide – Wiktionary