Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1001-26-9, is researched, Molecular C7H12O3, about Synthesis of the carbocyclic analogs of uracil nucleosides, the main research direction is nucleoside carbocyclic analog; uridine carbocyclic analog; leukemia treatment nucleoside.Application of 1001-26-9.
Treatment of hydroxyl derivatives of cis-3-aminocyclopentanemethanol with 3-ethoxyacryloyl isocyanate gave N-(3-ethoxyacryloyl)-N’-[hydroxy- or dihydroxy(hydroxymethyl)cyclopentyl]ureas. Cyclization of the ureas in dilute H2SO4 afforded high yields of the carbocyclic analogs I (R = OH, R1 = H; R = R1 = OH; R = H, R1 = OH) of uridine, 2′-deoxyuridine, and 3′-deoxyuridine. The uridine and 3′-deoxyuridine analogs were also obtained in good yields by cyclizing the ureas in concentrated aqueous NH3. None of the 3 analogs showed activity in tests vs. KB cells in culture or L1210 leukemia in vivo.
After consulting a lot of data, we found that this compound(1001-26-9)Application of 1001-26-9 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary