HPLC of Formula: 119707-74-3. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Synthesis and chromatographic evaluation of new polymeric chiral stationary phases based on three (1S,2S)-(-)-1,2-diphenylethylenediamine derivatives in HPLC and SFC. Author is Payagala, Tharanga; Wanigasekara, Eranda; Armstrong, Daniel W..
Three new polymeric chiral stationary phases were synthesized based on (1S,2S)-1,2-bis(2,4,6-trimethylphenyl)ethylenediamine, (1S,2S)-1,2-bis(2-chlorophenyl)ethylenediamine, and (1S,2S)-1,2-di-1-naphthylethylenediamine via a simple free-radical-initiated polymerization in solution These monomers are structurally related to (1S,2S)-1,2-diphenylethylenediamine which is the chiral monomer used for the com. P-CAP-DP polymeric chiral stationary phase (CSP). The performance of these three new chiral stationary phases were evaluated in normal phase HPLC and supercritical fluid chromatog. and the results were compared with those of the P-CAP-DP column. All three new phases showed enantioselectivity for a large number of racemates with a variety of functional groups, including amines, amides, alcs., amino acids, esters, imines, thiols, and sulfoxides. In normal phase, 68 compounds were separated with 28 baseline separations (Rs ≥ 1.5) and in SFC, 65 compounds were separated with 24 baseline separations In total 72 out of 100 racemates were separated by these CSPs with 37 baseline separations Complimentary separation capabilities were observed for many analytes. The new polymeric CSPs showed similar or better enantioselectivities compared with the com. column in both HPLC and SFC. However, faster separations were achieved on the new stationary phases. Also, these polymeric stationary phases have good sample loading capacities while maintaining enantioselectivity.
Although many compounds look similar to this compound(119707-74-3)HPLC of Formula: 119707-74-3, numerous studies have shown that this compound(SMILES:OC1=C(Br)C=C2C=CC=CC2=C1C3=C4C=CC=CC4=CC(Br)=C3O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary