The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 8-Bromooctanoic acid( cas:17696-11-6 ) is researched.Related Products of 17696-11-6.Fisher, Louise M.; Kim, Eliana E.; Moskalev, Nicolai V.; Gribble, Gordon W. published the article 《Asymmetric syntheses of potential anti-malarial drugs designed from Fieser’s 2-hydroxy-3-(2-methyloctyl)naphthalene-1,4-dione》 about this compound( cas:17696-11-6 ) in ARKIVOC (Gainesville, FL, United States). Keywords: naphthalene dione preparation antimalarial activity. Let’s learn more about this compound (cas:17696-11-6).
Asym. syntheses of the potential anti-malarial drugs (S)-2-(8-fluoro-2-methyloctyl)-3- hydroxynaphthalene-1,4-dione, (S)-2-hydroxy-3-(8-trifluoromethyl-2-methyloctyl)-3-hydroxynaphthalene-1,4-dione, and (S)-2-hydroxy-3-(2-methyloctyl)naphthalene-1,4-dione, which are patterned after Fieser’s ”10576”, known to be active against the mosquito borne parasite Plasmodium falciparum were described.
Although many compounds look similar to this compound(17696-11-6)Related Products of 17696-11-6, numerous studies have shown that this compound(SMILES:O=C(O)CCCCCCCBr), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary