The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 4,4-Dipyridyl Disulfide, is researched, Molecular C10H8N2S2, CAS is 2645-22-9, about The New Salicylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis, the main research direction is protein synthesis salcylaldehyde propanedithioacetal native chem ligation serine threonine; salcylaldehyde propanedithioacetal SPPS microwave NSL STL oxidation desulfurization; solid phase peptide synthesis reductive amination palmitoylation cyclization thiolysis; palmitoylated matrix ion channel influenza virus protein folding helix; interferon induced transmembrane protein palmitoylated synthesis.Application In Synthesis of 4,4-Dipyridyl Disulfide.
The combination of distinct peptide ligation techniques to facilitate chem. protein synthesis represents one of the long-standing goals in the field. A new combination ligation method of N-to-C sequential native chem. ligation and Ser/Thr ligation (NCL-STL) is described for the first time. This method relies on the peptide salcylaldehyde S,S-propanedithioacetal (SALPDT)-ester prepared by a new 1,3-propanedithiol-mediated reaction. The peptide SALPDT-ester, which is compatible with NCL, can be fully activated by N-chlorosuccinimide (NCS)/AgNO3 in aqueous solution to afford peptide SAL-ester for use in the subsequent STL. The practicality of the combined NCL-STL method is illustrated by the synthesis of S-palmitoylated matrix-2 ion channel from influenza A virus and S-palmitoylated interferon-induced transmembrane protein 3. This approach expands the multiple-segments peptide ligation toolkit for producing important and complex custom-made protein samples by chem. protein synthesis.
In some applications, this compound(2645-22-9)Application In Synthesis of 4,4-Dipyridyl Disulfide is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary