In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Boosting Enantioselectivity of Chiral Organocatalysts with Ultrathin Two-Dimensional Metal-Organic Framework Nanosheets, published in 2019-11-06, which mentions a compound: 119707-74-3, Name is (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, Molecular C20H12Br2O2, Electric Literature of C20H12Br2O2.
The development of methodologies for inducing and tailoring enantioselectivities of catalysts is an important issue in asym. catalysis. Chiral mol. catalysts can be boosted from completely nonselective to highly enantioselective when installed in nanostructured metal-organic frameworks (MOFs). Exfoliation of layered crystals is one of the most direct synthetic routes to ultrathin nanosheets, but its use in MOFs is limited by the availability of layered MOFs. The authors illustrate that layered MOFs can be designed using ligand-capped metal clusters and angular organic linkers. This gives two three-dimensional (3D) layered porous MOFs from Zn4-p-tert-butylsulfonyl calix[4]arene and chiral angular 1,1′-binaphthol/-biphenol dicarboxylic acids, which can be ultrasonic exfoliated into one- and two-layer nanosheets. The obtained MOF materials are efficient catalysts for asym. cascade condensation and cyclization of 2-aminobenzamide and aldehydes to produce 2,3-dihyroquinazolinones. While both binaphthol and biphenol display no enantioselectivity, restriction of their freedom in the MOFs leads to 56-90% and 46-72% ee, resp., which are increased to 72-94% and 64-82% ee after exposure to external surfaces of the flexible nanosheets. Moreover, the MOF crystals and nanosheets exhibit highly sensitive fluorescent enhancement in the presence of chiral amino alcs. with enantioselectivity factors being, resp., increased up to 1.4 and 2.3 times of the values of the diols, allowing them to be used in chiral sensing. Therefore, the observed enantioselectivities increase in the order organocatalyst < MOF crystals < MOF nanosheets in both catalysis and sensing. This work not only provides a strategy to make 3D layered MOFs and their ultrathin nanosheets but also paves the way to use nanostructured MOFs to manipulate enantioselectivities of mol. catalysts. This literature about this compound(119707-74-3)Electric Literature of C20H12Br2O2has given us a lot of inspiration, and I hope that the research on this compound((S)-3,3′-Dibromo-1,1′-bi-2-naphthol) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary