The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Ethyl 3-Ethoxy-2-Propenoate(SMILESS: O=C(OCC)/C=C/OCC,cas:1001-26-9) is researched.Product Details of 60804-74-2. The article 《Effect of hydroxyurea on α-acetylenic esters》 in relation to this compound, is published in Canadian Journal of Chemistry. Let’s take a look at the latest research on this compound (cas:1001-26-9).
Hydroxyurea, in its oxanion form NH2CONHO-, reacts in basic medium via 1,4-addition to α-acetylenic esters, leading to the E- and Z-ethylenic β-ureidoxy ester isomers. The Z isomer cyclizes in situ to give 2-carboxamido-5-methyl-3-isoxazolone. With HCCCO2Ph, 3-hydroxy-5-phenylisoxazole is directly obtained without isolating the intermediate N-carboxamido derivative HCCCO2Et gave 2 cyclic compounds: 3-hydroxyisoxazole (I) and 2-carboxamido-5-ethoxy-3-isoxazolidinone (II). I formation is due to the in situ cyclization of the Z isomer. II formation can be explained by solvent addition to the E-β-ureidoxyacrylate intermediate in a Michael addition, followed by cyclization.
In some applications, this compound(1001-26-9)COA of Formula: C7H12O3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary