Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 33216-52-3, is researched, Molecular C5H2Cl3N, about Radical Mediated C-H Functionalization of 3,6-Dichloropyridazine: Efficient Access to Novel Tetrahydropyridopyridazines, the main research direction is dichloropyridazine primary alc radical addition titanium trichloride tertbutyl hydroperoxide; chloropyridazinyl alkanol primary amine heterocyclization; tetrahydropyridopyridazine preparation mol crystal structure.Recommanded Product: 33216-52-3.
A radical mediated C-H functionalization of 3,6-dichloropyridazine using primary alcs., t-BuOOH, and TiCl3 to access alkoxy pyridazines is described. This transformation is conducted open to air and on gram scale. A subsequent cyclization step can then be employed to efficiently access diversely substituted tetrahydropyridopyridazines, e.g., I (X-rays single crystal structure shown), with multiple functional handles.
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Reference:
Bromide – Wikipedia,
bromide – Wiktionary