The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (2S)-1-[(4R)-4,5-dihydro-4-phenyl-2-oxazolyl]-2-(diphenylphosphino)ferrocene(SMILESS: [H]C12=C3([H])[Fe+2]145678(C3=C94C%10=N[C@H](C%11=CC=CC=C%11)CO%10)([C-]%12C5=C6C7=C8%12)[C-]92P(C%13=CC=CC=C%13)C%14=CC=CC=C%14,cas:291536-01-1) is researched.Reference of 7-Chloro-4-(piperazin-1-yl)quinoline. The article 《Chiral phosphine Lewis bases in catalytic, asymmetric aza-Morita-Baylis-Hillman reaction》 in relation to this compound, is published in Pure and Applied Chemistry. Let’s take a look at the latest research on this compound (cas:291536-01-1).
In the aza-Morita-Baylis-Hillman reaction of N-sulfonated imines with Me vinyl ketone (MVK) promoted by chiral phosphine Lewis base: (R)-2′-diphenylphosphanyl[1,1′]binaphthalenyl-2-ol (LB1) (10 mol %), the aza-Morita-Baylis-Hillman adducts were obtained in good yields with high ee (70-94 % ee) at -30 °C in THF. The scope and limitations of this reaction have been disclosed.
Here is just a brief introduction to this compound(291536-01-1)Electric Literature of C31H26FeNOP, more information about the compound((2S)-1-[(4R)-4,5-dihydro-4-phenyl-2-oxazolyl]-2-(diphenylphosphino)ferrocene) is in the article, you can click the link below.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary