Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3,4,5-Trichloropyridine, is researched, Molecular C5H2Cl3N, CAS is 33216-52-3, about Lewis Acidic Boranes, Lewis Bases, and Equilibrium Constants: A Reliable Scaffold for a Quantitative Lewis Acidity/Basicity Scale.Computed Properties of C5H2Cl3N.
A quant. Lewis acidity/basicity scale toward boron-centered Lewis acids has been developed based on a set of 90 exptl. equilibrium constants for the reactions of triarylboranes with various O-, N-, S-, and P-centered Lewis bases in dichloromethane at 20°. Anal. with the linear free energy relationship log KB = LAB+LBB allows equilibrium constants, KB, to be calculated for any type of borane/Lewis base combination through the sum of two descriptors, one for Lewis acidity (LAB) and one for Lewis basicity (LBB). The resulting Lewis acidity/basicity scale is independent of fixed reference acids/bases and valid for various types of trivalent boron-centered Lewis acids. It is demonstrated that the newly developed Lewis acidity/basicity scale is easily extendable through linear relationships with quantum-chem. calculated or common phys.-organic descriptors and known thermodn. data (ΔHBF3). Furthermore, this exptl. platform can be utilized for the rational development of borane-catalyzed reactions.
There is still a lot of research devoted to this compound(SMILES:C1=NC=C(C(=C1Cl)Cl)Cl)Computed Properties of C5H2Cl3N, and with the development of science, more effects of this compound(33216-52-3) can be discovered.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary