Application of 1219741-50-0. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 6-Bromo-3-methyl-1H-indole, is researched, Molecular C9H8BrN, CAS is 1219741-50-0, about Chiral Diphosphine-Palladium-Catalyzed Sequential Asymmetric Double-Friedel-Crafts Alkylation and N-Hemiketalization for Spiro-polycyclic Indole Derivatives. Author is Li, Nai-Kai; Zhang, Jun-Qi; Sun, Bing-Bing; Li, Hai-Yan; Wang, Xing-Wang.
An efficient cascade asym. Friedel-Crafts alkylation/N-hemiketalization/Friedel-Crafts alkylation reaction of 3-alkylindoles with oxindolyl β,γ-unsaturated α-ketoesters has been developed in the presence of a chiral diphosphine-palladium(II) catalyst. A series of enantiomerically enriched spiro-polycyclic indole derivatives, e.g. I, have been constructed in high yields with excellent enantioselectivities and diastereoselectivities.
There is still a lot of research devoted to this compound(SMILES：CC1=CNC2=C1C=CC(Br)=C2)Application of 1219741-50-0, and with the development of science, more effects of this compound(1219741-50-0) can be discovered.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary