Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 10016-52-1, name is 2,8-Dibromodibenzo[b,d]furan, A new synthetic method of this compound is introduced below., HPLC of Formula: C12H6Br2O
To a round bottom flask triphenylen-2-ylboronic acid 8.4g, 2,8-dibromodibenzo[b,d]furan 10.0g dissolved in toluene 280 ml K2CO3(2M) 46 ml and Pd(PPh3)4 1.1g After putting the mixture was stirred under reflux. Check the reaction by TLC and the reaction was terminated after addition of water. After the organic layer was extracted with MC and the residue was filtered under reduced pressure, re-crystallized to give an intermediate I1-1 8.1g (56% yield).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Dongjin SemiChem Co. Pvt. Ltd.; Ham, Ho-Wan; Kim, Bong-Ki; Kim, Seong-Hun; Ahn, Hyun-Chul; Kim, Hee-Ju; Kim, Dong-Jun; Lee, Hyung-Jin; Lim, Dong-Hwan; Ahn, Ja-Eun; (42 pag.)KR2016/80090; (2016); A;,
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