Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 43204-63-3, name is Bis(2-Bromoethyl)amine hydrobromide, A new synthetic method of this compound is introduced below., category: bromides-buliding-blocks
REFERENCE EXAMPLE 6 A mixture of di(2-bromoethyl)amine hydrobromide (15.6 g; 0.05 mol), 3-aminobenzotrifluoride (24.2 g; 0.15 mol) and methylethylketone (50 ml) was heated under reflux for 4 hours, and the resultant mixture was neutralized with a dilute sodium hydroxide solution and extracted with ether. The ethereal layer was washed with a saturated sodium chloride solution and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure, and the residue was distilled to give N-(alpha, alpha, alpha-trifluorom-tolyl)piperazine. B.P., 130-140 C./0.3 mmHg.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Sumitomo Chemical Company, Limited; US4598078; (1986); A;,
Bromide – Wikipedia,
bromide – Wiktionary