Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 60956-23-2, name is 1,2-Dibromo-4-methylbenzene, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 60956-23-2
Step A: 1,2-Dibromo-4-methyl-5-nitrobenzene 3,4-dibromotoluene (108.11 mL, 800 mmol) was added dropwise with mechanical stirring over 4 hours to nitric acid (90%, 280 mL, 6000 mmol) that was cooled to 0 C. under a nitrogen atmosphere. The internal temperature of the mixture was maintained below 10 C. during the addition and the reaction mixture was stirred for 1 hour at 0 C. after completion of addition. Water (840 mL) was added drop-wise to the mixture while maintaining the internal temperature below 10 C. The crude product was collected by filtration and washed with water (5*500 mL) to remove the excess nitric acid. The solids were dried under high vacuum and purified by recrystallization from ethanol (800 mL) to provide 180.9 g (77% yield) of the desired product as a solid. 1H NMR (400 MHz, CDCl3) delta 8.24 (s, 1H), 7.64 (s, 1H), 2.55 (s, 3H).
According to the analysis of related databases, 60956-23-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ARRAY BIOPHARMA INC.; US2006/264431; (2006); A1;,
Bromide – Wikipedia,
bromide – Wiktionary