In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 50548-45-3, name is 1-Bromodibenzo[b,d]furan belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. SDS of cas: 50548-45-3
To a 500 ml round bottom flask in a nitrogen atmosphereCompound 1-Bromobenzofuran (10.0 g, 40.65 mmol),N- (4- (triphenylene-2-yl) phenyl) – [1,1′-biphenyl] -4- amine(N- (4- (triphenylen-2-yl) phenyl) – [1,1′-biphenyl] -4-amine)(17.75 g, 44.72 mmol)Xylene(Xylene) in 320 mlAfter complete dissolution, sodium tert-butoxide(sodium tert-butoxide) (5.08 g, 52.85 mol), And bis (tri-tert-butylphosphine) palladium (0)(Bis (tri-tert-butylphosphine) palladium (0))(0.21 g, 0.41 mmol), and the mixture was heated with stirring for 3 hours. After the temperature was lowered to room temperature, the salt was removed by filtrationXylene was concentrated under reduced pressure and recrystallized from 180 ml of tetrahydrofuran to obtain the above compound 5 (17.75 g, yield:68percent).
The synthetic route of 50548-45-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; LG CHEM, LTD.; KIM, Jin Joo; HONG, Sung gil; CHA, Yong bum; (27 pag.)KR2017/94665; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary