Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 53078-85-6, name is 2-Bromo-5-methylaniline, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 53078-85-6
3-phenyl-2,2-dihydroxy-3-oxopropionic acid ethyl ester (0.05 mmol) was added to the reaction flask.2-bromo-5-methylaniline (0.05 mmol),4-phenyl-1,3-cyclohexanedione (0.05 mmol),(R)-3,3,3′,3′-tetramethylspirophosphoric acid (0.005 mmol) represented by the formula (V),Anhydrous Na2SO4 (200 mg) was poured into 1 mL of dichloromethane, and the mixture was reacted at 65 C for 16 hours. After completion of the reaction, the column was directly subjected to silica gel column chromatography, and the eluent was ethyl acetate / petroleum ether = 1:30.Corresponding optically active 1-arylindole derivative (I-7), yield 73%;
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 53078-85-6.
Reference:
Patent; Zhejiang University; Lin Xufeng; Wang Lei; Zhong Jialing; (14 pag.)CN110183373; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary