Related Products of 4549-33-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4549-33-1, name is 1,9-Dibromononane belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Take a 50 mL flask, install a reflux condenser, and add 2.0 mL (12.56 mmol) of 2,3,3-trimethyl-3H-indole.2.55 mL of 1,9-dibromodecane (12.56 mmol) and 20 mL of tetrahydrofuran, heated to reflux for 24 hours;Stop heating and allow the reaction system to cool to room temperature;704.7 mg (12.56 mmol) of potassium hydroxide and 2.1 g (12.56 mmol) of 5-nitrosalicylaldehyde were sequentially added to the above system, and the reaction was further continued for 10 minutes.The system is neutralized with acid, washed, extracted, and the solvent is dried.The product was purified by silica gel column chromatography (eluent petroleum ether / ethyl acetate).A yellow solid was obtained in an amount of 1.93 g, yield 30%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,9-Dibromononane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Qingdao University of Science and Technology; Deng Yawen; Xie Congxia; Wu Zhongtao; Zhang Lei; (6 pag.)CN110028517; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary