Application of 2576-47-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2576-47-8, name is 2-Bromoethylamine hydrobromide belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: A mixture of aniline (or PhNHEt) (0.05 mol)), 2-bromoethyl- (or 3-bromopropyl)amine hydrobromide and water (6 mL) was heated to 95 C (ina bath), Then, NaHCO3 was added in small portions with stirring. After ~15 min (at 95 C), the reaction mixture was refluxed with stirring using a heating mantle until reaction reached completion. The amount of hydrobromide and NaHCO3 and the timeof heating are given in Table 1. Still warm reaction mixture was diluted with 50% aqueous KOH (11 mL) and water (16 mL). The organic layer was separated, the aqueous layer was saturated with NaCl and extracted with chloroform (4×20 mL), each timeadding NaCl into the aqueous phase. The combined organic layers were dried with MgSO4 and fractionally distilled in vacuo.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Bromoethylamine hydrobromide, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Vasilyeva; Vorobyeva; Osipov; Russian Chemical Bulletin; vol. 65; 9; (2016); p. 2211 – 2215; Izv. Akad. Nauk, Ser. Khim.; 9; (2016); p. 2211 – 2215,5;,
Bromide – Wikipedia,
bromide – Wiktionary