Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 59734-92-8, name is 1-Bromo-2-cyclohexylbenzene, This compound has unique chemical properties. The synthetic route is as follows., category: bromides-buliding-blocks
A Schlenk tube was charged with Cul (9.6 mg, 0.050 mmol, 5.0 mol%), NaI (300 mg, 2.00 mmol), evacuated and backfilled with argon. Racemic [TRANS-N, N’-DIMETHYL-1,] 2- cyclohexanediamine (16 RL, 0.10 mmol, 10 mol%), 1-bromo-2-cyclohexylbenzene (97% pure; Lancaster; 186 [(IL,] 1.00 mmol), n-pentanol (1 mL) were added under argon. The Schlenk tube was sealed with a Teflon valve and the reaction mixture was stirred at [130 C] for 40 h. The resulting suspension was allowed to reach room temperature and filtered through silica gel (1 x0. 5 cm) eluting with hexane (50 mL). The filtrate was concentrated, and the residue was purified by flash chromatography on silica gel (hexane) to provide the known [1-IODO-2-CYCLOHEXYLBENZENE] (283 mg, 99% yield; ca. 97% pure) as a colorless liquid. [SEE MCGUINE,] T. H.; Dull, M. F. J. Am. [CHEM. SOC.] 1947, 69, [1469.’H NMR] (400 MHz, [CDC13)] : 8 7. 85 (dd, [J= 7.] 5,1. [2 HZ,] 1H), 7.32 (td, J= 7.5, 1. [2 HZ,] 1H), 7.23 (dd, [J= 7.] 5,1. [7 HZ,] 1H), 6.90 [(TD,] [J= 7.] 5,1. [7 HZ,] 1H), 2.81 (tt, J= 11.7, 3. [0 HZ, 1H),] 1.97-1. 74 (m, [5H),] 1.55-1. 23 (m, [5H).] [13CNMR] (100 MHz, [CDC13)] : 8 149.3, 139.5, 128.4, 127.6, 126.6, 101.5, 48. 5,33. 4,26. 8,26. 1.
According to the analysis of related databases, 59734-92-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MASSACHUSETTS INSTITUTE OF TECHNOLOGY; WO2004/13094; (2004); A2;,
Bromide – Wikipedia,
bromide – Wiktionary