Synthetic Route of 2695-47-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2695-47-8, name is 6-Bromo-1-hexene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Synthesis of 2-(4-bromobutyl)-oxirane (I): A Solution of 3- Chloroperbenzoic acid (55-75% pure, 4.54 g, 18.39 mmol) in 20 ml dichloromethane was added dropwise to a stirred solution of 6-bromo-l-hexne (2g, 12.26 mmol) in 20 ml of dichioromethane. After addition, the mixture was stirred at 25 C for 16h, to precipitate 3-chiorobenzoic acid. Finally the reaction mixture was evaporated to dryness under vacuum, dissolved in ethyl acetate, washed initially with 4% sodium dithionate followed by saturated sodium bicarbonate and water. Finally the organic layer was dried over sodium sulphate, evaporated and dried under vacuo to obtain the final compound (I) with 90% isolated yield. -NMR (400 MHz, CDC13) delta ppm: -NMR (400 MHz, CDC13) delta ppm: 1 .48- 1 .6(6H, m, CH2) 2.47 ( 1 H, d, J = 2.4, OCH) 2.75 (t, J = 4, 1 H, OCHb), 2.91 (bs, 1 H, OCHa) 3.41 (t, J = 6.4, 2H, CH2-Br) .
The synthetic route of 6-Bromo-1-hexene has been constantly updated, and we look forward to future research findings.
Reference:
Patent; VYOME BIOSCIENCES PVT. LTD.; SENGUPTA, Shiladitya; CHAWRAI, Suresh Rameshlal; GHOSH, Shamik; GHOSH, Sumana; JAIN, Nilu; SADHASIVAM, Suresh; BUCHTA, Richard; BHATTACHARYYA, Anamika; WO2015/114666; (2015); A2;,
Bromide – Wikipedia,
bromide – Wiktionary