Reference of 1435-53-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1435-53-6, name is 2,4-Dibromo-1-fluorobenzene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Dibromofluorobenzene (1.0 g, 4.0 mmol), sodium methanethiolate (0.33 g, 4.8 mmol) and triethylamine (0.52 mL, 4.0 mmol) were dissolved in a flask charged with 3 mL of N,N-dimethylacetamide in a sealed tube and heated to 100 C for 12 hours. After the reaction was completed, the reaction solution was cooled to room temperature, extracted with ethyl acetate, washed with brine, dried over anhydrous magnesium sulfate and passed through a silica gel column (ethyl acetate / n-hexane) to give an oily liquid (0.65 g, 58%).
The synthetic route of 2,4-Dibromo-1-fluorobenzene has been constantly updated, and we look forward to future research findings.
Reference:
Patent; South China University of Technology; Yang Wei; Yang Yong; Zhang Bin; Wu Hongbin; Cao Yong; (32 pag.)CN105001233; (2017); B;,
Bromide – Wikipedia,
bromide – Wiktionary