Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4549-33-1, name is 1,9-Dibromononane, This compound has unique chemical properties. The synthetic route is as follows., category: bromides-buliding-blocks
Preparation 103 (R)-4-(Biphenyl-2-ylcarbamoyloxy)-1-(9-bromononyl)-1-azoniabicyclo[3.2.1]octane Bromide To a stirred solution of the product of Preparation 102 (1.21 g, 3.76 mmol) and triethylamine (1.05 ML, 7.52 mmol) in acetonitrile (18.8 ML) was added 1,9-dibromononane (994 muL, 4.89 mmol) and the reaction mixture was heated at 50 C. for 4 h.The reaction mixture was then cooled and the solvent was removed under reduced pressure.The residue was dissolved in dichloromethane (20 ML) and the organic layer was washed with saturated aqueous sodium bicarbonate (10 ML), dried (magnesium sulfate) and solvent removed under reduced pressure.The crude product was purified by flash chromatography (10% methanol/dichloromethane, 0.5% ammonium hydroxide) to give the title compound (1.04 g, 1.97 mmol, 52% yield).
According to the analysis of related databases, 4549-33-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Mammen, Mathai; Dunham, Sarah; Hughes, Adam; Lee, Tae Weon; Husfeld, Cralg; Stangeland, Eric; US2004/167167; (2004); A1;,
Bromide – Wikipedia,
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