Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 16518-62-0, name is 3-Bromo-N,N-dimethylaniline, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 16518-62-0
3-Bromo-/V,/V-dimethylaniline (13) (3.20 g, 16.00 mmol, 2.0 eq.) was dissolved in dry Et20 (45 mL) and cooled down to -78 C. sec-BuLi (14.0 mL, 18.40 mmol, 2.3 eq., 1.3 M in cyclohexane) was added dropwise over 15 min and the mixture was stirred for 30 min at – 78 C. Dichlorodimethylsilane (14) (1.0 mL, 8.00 mmol, 1.0 eq.) was added dropwise over 10 min at -78 C. The mixture was stirred for 10 min at -78 C and then warmed up to room temperature and stirred for 1 h. The mixture was quenched with aqueous saturated NaHCC>3 solution. The aqueous layer was extracted with Et20 (3 x 150 mL) and the combined organic layers were dried over MgS04, filtered and evaporated to afford the crude product.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 16518-62-0.
Reference:
Patent; SPIROCHROME AG; JOHNSSON, Kai; REYMOND, Luc; FREI, Michelle; PITSCH, Stefan; (71 pag.)WO2019/122269; (2019); A1;,
Bromide – Wikipedia,
bromide – Wiktionary