These common heterocyclic compound, 955959-84-9, name is 4-(4-Bromophenyl)dibenzo[b,d]furan, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Safety of 4-(4-Bromophenyl)dibenzo[b,d]furan
Under an argon atmosphere, the intermediate body 3H-1 (2.36 g, 7.3 mmol), an intermediate body 3H-2 (3.0 g, 7.3 mmol), CuI (1.4 g, 7.3 mmol), tripotassium phosphate (2.3 g, 11 mmol), anhydrous dioxane (30 mL), and cyclohexanediamine (0.84 g, 7.3 mmol) were loaded in the stated order into a three-necked flask, and were then stirred at 100 C. for 8 hours. Water was added to the reaction liquid to precipitate a solid, and then the solid was washed with hexane and then with methanol. Further, the resultant solid was purified by silica gel column chromatography. Thus, a compound 3H (2.9 g, 60% yield) was obtained. The result of FD-MS analysis confirmed that the compound had a ratio m/e of 650 with respect to its molecular weight, i.e., 650.
The synthetic route of 4-(4-Bromophenyl)dibenzo[b,d]furan has been constantly updated, and we look forward to future research findings.
Reference:
Patent; IDEMITSU KOSAN CO. LTD.; UNIVERSAL DISPLAY CORPORATION; Yamamoto, Hitoshi; Weaver, Michael S.; Brown, Julia J.; Nishimura, Kazuki; Iwakuma, Toshihiro; (76 pag.)US9966541; (2018); B2;,
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