Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 18599-22-9, name is 4-Bromo-3,3,4,4-tetrafluorobut-1-ene, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 4-Bromo-3,3,4,4-tetrafluorobut-1-ene
Under an argon atmosphere, methyl lithium-diethyl ether solution (1.0 M, 2.2 mL) without containing lithium bromide was dropped to tetrahydrofuran solution (2.0 mL) of 4-bromo-3,3,4,4-tetrafluoro-1-butene (0.23 g, 1.1 mmol) and 4- (trans-4-propylcyclohexyl) benzaldehyde (0.55 g, 2.4 mmol) at -78 C and stirred for 2 hours. After that, saturated ammonium chloride aqueous solution was poured into the reaction solution and reaction was stopped. The reaction solution was extracted three times with ethyl acetate, the obtained organic layer was dried with anhydrous sodium sulfate. After drying, filtration was carried out, and the obtained filtrate was concentrated with rotary evaporator. After that, the residue was purified by silica gel column chromatography (hexane / ethyl acetate = 7/1), compound (9-B) was obtained. (0.32 g, 0.88 mmol, 81% yield)
According to the analysis of related databases, 18599-22-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; AGC Seimi Chemical Co., Ltd.; Konno, Tsutomu; Ishihara, Takashi; Asai, Tomoyuki; (24 pag.)JP2016/84300; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary