Adding a certain compound to certain chemical reactions, such as: 88223-35-2, name is 2-Bromo-9,9-dibutyl-9H-fluorene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 88223-35-2, name: 2-Bromo-9,9-dibutyl-9H-fluorene
General procedure: 2-Bromo-9,9-dialkylfluorene (10.0 mmol, 1a, 1b or 1c) was dissolved in CH2Cl2 (60 mL), in the presence of a supported catalystof SiO2/H2SO4 (4.60 g) prepared according to the literature procedure.31 HNO3 (417 mL, 10.0 mmol) was added, and the heterogeneous mixture was stirred at room temperature for 10 min. The solution was then filtered, and the filtrate was washed with aqueous saturated NaHCO3 solution (10 mL) and water (10 mL). The organic layer was dried over anhydrous MgSO4 and the solvent was evaporated under reduced pressure.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-Bromo-9,9-dibutyl-9H-fluorene, and friends who are interested can also refer to it.
Reference:
Article; Lazar, Laszlo; Nagy, Miklos; Racz, David; Zsuga, Miklos; Keki, Sandor; Tetrahedron; vol. 70; 23; (2014); p. 3691 – 3699;,
Bromide – Wikipedia,
bromide – Wiktionary