Adding a certain compound to certain chemical reactions, such as: 52997-43-0, name is 7-(Bromomethyl)pentadecane, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 52997-43-0, Computed Properties of C16H33Br
TPh (1.6 g, 5.3 mmol), potassium carbonate (3.68 g, 26.7 mmol), potassium iodide (0.044 g, 0.3 mmol) and N, N-dimethylformamide (hereinafter abbreviated as ” DMF) (10 mL) and stirred at room temperature. Then 2-n-hexyl-1-bromodecane (2.1 g, 6.9 mmol) was added dropwise. After completion of the dropwise addition at room temperature overnight. After the reaction was completed, the mixture was extracted with water and methylene chloride and concentrated. Separation and purification on a silica gel column gave 1.23 g of 1- (2-hexyldecyl) -2- (thiophen-2-yl) -1H-phenan- thro [9,10- (Hereinafter referred to as TPh-C16). Yield 50.2%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 7-(Bromomethyl)pentadecane, and friends who are interested can also refer to it.
Reference:
Patent; Nanjing University of Posts and Telecommunications; Wang Lianhui; Zhao Baomin; Zhai Liuqing; He Cong; Wang Suiliang; Fu Nina; (11 pag.)CN105820169; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary