4549-33-1, name is 1,9-Dibromononane, belongs to bromides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Application In Synthesis of 1,9-Dibromononane
EXAMPLE 4 N, N’-Nonane-1, 9-diyl-bis-pyridinium Dibromide (bPNB).; 1,9-Dibromononane (mmol) was added to a solution (30 mL) of dry pyridine, and the solution heated for 24 hours at 65C. The resulting precipitate was filtered, and the product washed five times with dry diethyl ether. The resulting clear liquid was isolated in a 87% yield. ‘H NMR (300 MHz, DMSO-D6) 5 9.17 (2H, d, C2&C6-H), 8.61 (1H, t, C4-H), 8. 18 (2H, t, C3&C5-H), 4.63 (2H, t, C’1-CH2), 1.89 (2H, m, C’2-CH2), 1.22 (5H, m, C’3-5-CH2) ; 13C NMR (75 MHz, DMSO-D6) 8 145.3, 144.5, 127.9, 60.5, 30.7, 28.4, 28.2, 25.3.
The synthetic route of 4549-33-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION; WO2005/66129; (2005); A2;,
Bromide – Wikipedia,
bromide – Wiktionary