Synthetic Route of 4101-68-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4101-68-2, name is 1,10-Dibromodecan, This compound has unique chemical properties. The synthetic route is as follows.
To a stirred suspension of salicyaldehyde (2 mL, 20 mmol) and potassiumcarbonate (5.52 g, 40 mmol) in DMF (100 mL) was added 1,10-dibromodecane (10.8mL, 48 mmol). The mixture was stirred at 80 C for 3 h, and the solvent was evaporated under reducedpressure. The resulting residue was triturated with ether (1000 mL), and theorganic phase was washed with dilute sodium hydroxide solution, water, brine,and dried over sodium sulfate. After evaporation of the solvent, the residuewas purified by column chromatography (petroleum/ethyl acetate, 20:1), toafford compound 2 (2.45 g, 36%) as an oil. 1H NMR(300 M,CDCl3): d 1.31-1.46 (m, 12 H), 1.82-1.87 (p, 4 H), 3.41 (t, J =6.90 Hz, 2 H), 4.07 (t, J = 6.30 Hz, 2 H), 6.99 (m, 2 H), 7.52 (m, 1 H), 7.81(m, 1 H), 10.50 (s, 1 H). MS (EI) (m/e): 340 (M-H+). Anal. Calcd forC17H25BrO2: C, 59.83%; H, 7.38%; O, 9.38%.Found: C, 59.32%; H, 7.98%.
The chemical industry reduces the impact on the environment during synthesis 1,10-Dibromodecan. I believe this compound will play a more active role in future production and life.
Reference:
Article; Liu, Hui; Li, Zhan-Ting; Chinese Chemical Letters; vol. 25; 5; (2014); p. 659 – 662;,
Bromide – Wikipedia,
bromide – Wiktionary