Reference of 15155-41-6, A common heterocyclic compound, 15155-41-6, name is 4,7-Dibromo-2,1,3-benzothiadiazole, molecular formula is C6H2Br2N2S, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
In two 250mL flask, followed by adding ethanol 150ml, 2,5- dibromo benzothiadiazole (5. 88g, 20mmol), the flask was placed in an ice-water bath, sodium borohydride was slowly added repeatedly (1. 52g, 40mmol after), 0 C reaction lOmin, room temperature, the reaction 3h, the reaction was completed. After rotary evaporation to dryness in vacuo purified by column chromatography, petroleum ether: dichloromethane = 1: 1 to giveOff-white product 5. 05g (95% yield).
The synthetic route of 15155-41-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; NanjingFriend Photoelectric Technology Co., Ltd; MENG, HONG; ZHANG, XIAOTAO; YUAN, XIAO; YAN, LIJIA; (10 pag.)CN103450226; (2016); B;,
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