Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3814-30-0, name is (Bromomethyl)cyclopentane, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 3814-30-0
A mixture of Compound 74A (5 g, 30.6 mmol), (bromomethyl)cyclopentane (10 g, 61.3 mmol), and C52CO3 (30 g, 92 mmol) in DMF (100 mL) was stirred at room temperature for 18 hours. The reaction mixture was treated with H20 (50 mL) and ethyl acetate (50 mL), washed with water (500 mL x 3), dried over anhydrous sodium sulfate, filtered, and concentrated. The crude product was purified by silica gel column chromatography to furnish Compound 74B and Compound 74C.Compound 74B: LC-MS (ESI) m/z: 246 [M+H] ?H-NMR (CDC13, 400 IVIHz): (5(ppm) 1.30-1.31 (m, 2H), 1.57-1.60 (m, 2H), 1.58-1.78 (m, 4H), 2.55-2.59 (m, 1H), 4.39 (d, J 7.6 Hz, 2H), 7.75 (d, J 9.6 Hz, 1H), 8.10 (d, J= 9.6 Hz, 1H), 8.21 (s, 1H), 8.73 (s, 1H). Compound 74C: LC-MS (ESI) m/z: 246 [M+H] ?H-NIVIR (CDC13, 400 IVIHz): (5(ppm) 0.80-0.89 (m, 2H), 1.26-1.36 (m, 2H), 1.60-1.78 (m, 4H), 2.63-2.65 (m, 1H), 4.39 (d, J 7.6 Hz, 2H), 7.75 (d, J 9.6 Hz, 1H), 8.10 (d, J= 9.6 Hz, 1H), 8.21 (s, 1H), 8.73 (s, 1H).
According to the analysis of related databases, 3814-30-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BIOMARIN PHARMACEUTICAL INC.; WANG, Bing; (377 pag.)WO2018/118838; (2018); A1;,
Bromide – Wikipedia,
bromide – Wiktionary