Adding a certain compound to certain chemical reactions, such as: 327-52-6, name is 1-Bromo-2,4,5-trifluorobenzene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 327-52-6, Quality Control of 1-Bromo-2,4,5-trifluorobenzene
To magnesium spalls in a reaction flask, under an atmosphere of nitrogen, was added 50 ml tetrahydrofuran and 0.02 g iodine as an initiator. A solution of 9g 1-bromo-2,4,5-trifluorobenzene in 150ml tetrahydrofuran was added dropwise into the reaction system. The reaction was stirred at 25 C for 3h to obtain a solution of 0.21 mol/L (2, 4, 5-trifluorophenyl)-magnesium bromide.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Bromo-2,4,5-trifluorobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Zhejiang Jiuzhou Pharmaceutical Co., Ltd.; GAO, Hongjun; LI, Min; EP2551259; (2013); A1;,
Bromide – Wikipedia,
bromide – Wiktionary