Related Products of 86845-27-4, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 86845-27-4, name is 5-Bromo-2-methylbenzotrifluoride, This compound has unique chemical properties. The synthetic route is as follows.
III.2; [4-bromo-2-(trifluoromethyl)phenyl] acetonitrile; Step 1 : 4-bromo-l-(bromomethyl)-2-(trifluoromethyl) benzene; A solution of commercially available 4-bromo-l -methyl -2 -(trifiuorornethyl)benzene (1 eq.), NBS (1.1 eq.) and a catalytic amount of benzoyl peroxide in CCl4 (0.21M) was stirred at room temperature for Ih under a 150W spot lamp. The mixture was concentrated, purification by column chromatography on silica gel, eluting with Hex, afforded the desired material as an oil.
The chemical industry reduces the impact on the environment during synthesis 5-Bromo-2-methylbenzotrifluoride. I believe this compound will play a more active role in future production and life.
Reference:
Patent; MERCK FROSST CANADA LTD.; WO2009/23964; (2009); A1;,
Bromide – Wikipedia,
bromide – Wiktionary