2862-39-7, name is 2-Bromo-N,N-dimethylethanamine hydrobromide, belongs to bromides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C4H11Br2N
The product (60mg, 0.17mmol) in 127 cases of [0479] embodiment taken dissolved in N, N- dimethylformamide (DMF, IOmL) was added cesium carbonate (125mg, 0.38mmol) and N, N- dimethyl amine bromoethane hydrobromide (45mg, 0.19mmol), 50 C oil bath and the reaction overnight, TLC detection, the reaction was complete, water chestnut evaporated to dryness and dissolved. (/=15:1)-1 (3 (2-(-5 (34–2-49mg70%) Column chromatography (dichloromethane / methanol = 15: 1) to give the product -1 (3 (2- (dimethylamino) ethoxy) benzyl) -5- (3,4-dimethoxybenzyl) pyrrolidin-2-one (49mg, 70%).
The synthetic route of 2862-39-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Hu Youhong; Leng Ying; Duan Shudong; Huang Suling; (120 pag.)CN103626713; (2017); B;,
Bromide – Wikipedia,
bromide – Wiktionary