Adding a certain compound to certain chemical reactions, such as: 314084-61-2, name is 2-Bromo-1,3-diethyl-5-methylbenzene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 314084-61-2, Product Details of 314084-61-2
In a 250 mL four-necked reaction flask equipped with a stirrer, thermometer, condenser,32.0 g (0.2 mol)Diethyl malonate, 16 g (0.4 mol) of sodium hydroxide and 100 mL of N-methylpyrrolidone. (0.11111) 2,6-diethyl-4-methyl bromobenzene and 1.28 cuprous bromide were added to a solution of 120 to 130 C for 10 h. Cool, then remove the solvent under negative pressure at 0.095 MPa, 90 C, add 200 g of 7K, adjust the pH to 3 with hydrochloric acid, extract with 3 x 80 mL of ethyl acetate, wash with 3X, 150 mL water, 1 OmL was calcined and crystallized by filtration, washed with n-hexane to give 22.9 g of a pale yellow solid in 75% yield.sodium hydroxideDefinitions of sodium hydroxidenouna strongly alkaline white deliquescent compound used in many industrial processes, e.g., the manufacture of soap and paper.Primary alkaline batteries use sodium hydroxide or potassium hydroxide as the electrolyte.See alsosodium, hydroxideGoogle Translate for Business:Translator ToolkitWebsite Translator
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-Bromo-1,3-diethyl-5-methylbenzene, and friends who are interested can also refer to it.
Reference:
Patent; Wuhan Institute of Technology; Liu Anchang; Dong Yuanhai; Yu Yu; Zheng Yiqian; Wang Yanlu; (10 pag.)CN106928253; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary