Synthetic Route of 3814-30-0, The chemical industry reduces the impact on the environment during synthesis 3814-30-0, name is (Bromomethyl)cyclopentane, I believe this compound will play a more active role in future production and life.
EXAMPLE 2 Preparation of 1-cyclopentylmethylimidazole Imidazole (6.8 g, 0.1 mol) was added to a solution of sodium (2.3 g, 0.1 mol) in dry ethanol (100 ml). This solution was stirred and heated to reflux when bromomethylcyclopentane (16.3 g, 0.1 mol) was added dropwise. Following the addition, the mixture was stirred and heated under reflux for 16 h. After cooling, the reaction mixture was filtered and the filtrate concentrated under reduced pressure. The residue was dissolved in 2 M-hydrochloric acid (150 ml) and the solution washed with ether. The aqueous solution was basified with 10 M-sodium hydroxide solution, and the product extracted with chloroform (3*50 ml). The extracts were combined, dried (MgSO4), and the solution concentrated to afford a yellow oil. The oil was purified using a silica gel column and elution with ethyl acetate/methanol (9:1). The product fractions were combined and concentrated under reduced pressure to afford 1-cyclopentylmethylimidazole (1.9 g), which was further purified by distillation, b.p. 68-69/0.125 mmHg.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (Bromomethyl)cyclopentane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Burroughs Wellcome Co.; US4317830; (1982); A;,
Bromide – Wikipedia,
bromide – Wiktionary